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1.
HLA ; 103(1): e15328, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-38174647

RESUMO

One nucleotide substitution in codon 83 of HLA-С*12:02:02:01 results in the novel allele, HLA-C*12:392.


Assuntos
Medula Óssea , Antígenos HLA-C , Humanos , Antígenos HLA-C/genética , Alelos , Éxons/genética , Códon , Doadores de Tecidos , Teste de Histocompatibilidade , Doadores não Relacionados
2.
HLA ; 103(1): e15304, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37990789

RESUMO

One nucleotide substitution in codon 211 of HLA-A*29:01:01:01 results in the novel HLA-A*29:183 allele.


Assuntos
Alelos , Antígenos HLA-A , Humanos , Federação Russa
3.
Genes (Basel) ; 11(12)2020 12 09.
Artigo em Inglês | MEDLINE | ID: mdl-33317063

RESUMO

Nuclear pollution is an urgent environmental issue and is a consequence of rapid industrialization and nuclear accidents in the past. Remediation of nuclear polluted sites using microbial vital activity (bioremediation) is a promising approach to recover contaminated areas in an environmentally friendly and cost-saving way. At the same time, the number of known bacterial and archaeal species able to withstand extremely high doses of ionizing radiation (IR) is steadily growing every year, together with growing knowledge about mechanisms of radioresistance that opens up opportunities for developing new biotechnological solutions. However, these data are often not systemized, and can be difficult to access. Here, we present the Determinants of Radioresistance Database, or DetR DB, gathering a comprehensive catalog of radioresistant microbes and their molecular and genetic determinants of enhanced IR tolerance. The database provides search tools, including taxonomy, common gene name, and BLAST. DetR DB will be a useful tool for the research community by facilitating the extraction of the necessary information to help further analysis of radiation-resistant mechanisms.


Assuntos
Archaea/efeitos da radiação , Bactérias/efeitos da radiação , Bases de Dados Factuais , Tolerância a Radiação/genética , Archaea/genética , Bactérias/genética , Biodegradação Ambiental/efeitos da radiação , Poluentes Ambientais , Tolerância a Radiação/fisiologia , Radiação Ionizante
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